About this property

The Twentyone is a modern boutique hotel on Via Cola di Rienzo, one of Rome's best shopping streets. Castel Sant'Angelo and the historic center are just a pleasant 10-minute walk away. Rooms at the Twentyone Hotel are ultra modern and feature a minimalist décor. They offer an LCD satellite TV, air conditioning, mini-bar, and free WiFi. In the breakfast room located on the roof, where you can enjoy the city view, a breakfast buffet awaits you every morning. Open for lunch and dinner, the on-site restaurant serves traditional Roman and classic Italian dishes and a large selection of wines and champagne. Inside the hotel there is a Starbucks which Guests can access directly and where they can have breakfast. The hotel is in the elegant Prati district, home to the Vatican and Saint Peter's Basilica, which are a 15-minute walk away. Lepanto Metro Station is 1476 feet from the property, while bus links to Roma Termini Train Station are located close by.

Couples in particular like the location – they rated it 9.2 for a two-person trip.

Distance in property description is calculated using © OpenStreetMap

Property highlights

    • Perfect for a 3-night stay!

    • Located in the heart of Rome, this hotel has an excellent location score of 9.2

    • Top pick by families with children

    • Breakfast Info

    • Continental, American

    • Private parking at the hotel


 ! 

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Availability

Prices converted to FJD
We have no availability here between Mon, Sep 15, 2025 and Thu, Sep 18, 2025.

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1 queen bed
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3 twin beds
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2 twin beds
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Limited supply in Rome for your dates: 15 four-star hotels like this are already unavailable on our site

Guest reviews

Categories:

Staff
Facilities
Cleanliness
Comfort
Value for money
Location
Free Wifi

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Guests who stayed here loved

  • Albert
    United States United States
    We had a great included breakfast and safely walked to different restaurants for dinner. On our early morning exit day, they even prepared a boxed breakfast for us to take with us to the airport.
  • Smaranda
    Norway Norway
    Central and close to many of the sights, nice and clean rooms, good bed, and with working air conditioning.Friendly and helpful staff.Fantastic breakfast on the rooftop restaurant.
  • Vittorio
    United States United States
    location was awesome -- close to downtown and touristic area. room not very spacious but clean and confortable. staff very helpful and kind breakfast on rooftop -- awesome!
  • Temirlan
    Kazakhstan Kazakhstan
    Best breakfast meals and panoramic view. Good cappucino and crossaint Clean Polite staff Close to Vatican and other touristic places Luggage carry Wi-Fi
  • Dileepa
    Canada Canada
    The location was perfect for my little vacation in Rome
  • Ibrahim
    Turkey Turkey
    The location was excellent, the room was clean, and the staff was helpful and kind.
  • James
    United States United States
    The room was amazing, the view from our room was incredible. The breakfast was also great with plenty of choices and very well staffed. The front desk staff were very professional. We would return in a heartbeat.
  • Shelby
    Canada Canada
    How centrally located it is. The hotel is clean and the staff are friendly and helpful.
  • Carolyn
    United States United States
    The location of the hotel was perfect! We were close to the Vatican and plenty of shops, restaurants, etc. I felt safe walking around and the view from the restaurant at the top was fabulous.
  • Alexandre
    United States United States
    the location was extraordinary, near metro, restaurants, The Vaticano.

Hotel area info

Restaurants

1 Restaurant On Site
  • Vista
    • Cuisine
      International
    • Ambience
      Modern
    • Dietary options
      Vegetarian

House rules

Twentyone Hotel takes special requests – add in the next step!
Check-in
From 3:00 PM to 12:00 AM
Check-out
From 7:00 AM to 11:00 AM
Cancellation/ prepayment
Cancellation and prepayment policies vary according to accommodation type. Check what conditions apply to each option when making your selection.
Children & Beds

Child policies

Children of all ages are welcome.

To see correct prices and occupancy info, add the number and ages of children in your group to your search.

Crib and extra bed policies

The number of cribs allowed depends on the option you choose. Check your selected option for more info.

There are no extra beds available at this property.

All cribs are subject to availability.

No age restriction
There's no age requirement for check-in
Pets
Pets are not allowed.
Groups
When booking more than 4 rooms, different policies and additional fees may apply.
Accepted payment methods
American ExpressVisaCartaSiCash

The fine print

Must-know information for guests at this property

Please note that parking spaces are limited and subject to availability.

In response to the coronavirus (COVID-19), additional safety and sanitation measures are in effect at this property.

License number: 058091-ALB-00313, IT058091A1GZ5MCI9I